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Chem Res Toxicol 16:295303 Coen M, Ruepp SU, Lindon JC, Nicholson JK, Pognan F, Lenz EM, Wilson ID (2004) Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

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If tap water is used, it should be treated or tested to remove harmful metals and ammonia