Insider's takeaway The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements
In label language, bac water means bacteriostatic water, a sterile water preparation that contains benzyl alcohol as a preservative
They consider the patients health history, how severe the deficiency is, and any conditions that might affect how well the body absorbs B12
However, the repeated or continuous inflammatory and demyelinating processes plus endogenous attempts for remyelination and repair increase vitamin B12 consumption and may lead to its deficiency
The payment limit per the CMS ASP drug pricing is the allowable for Medicare Part B claims
Which formulations, if any, carry higher rates of specific adverse events