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Create a plan with your doctor to address possible rebound effects before stopping

The video ends with a reminder to stay consistent, even though the whole premise suggests an instant effect

Dysesthesia: A New Signal for Retatrutide The TRIUMPH-4 Phase 3 trial revealed an unexpected finding: dysesthesia (abnormal touch sensations where normal sensations feel unusual or painful) in 20.9% of participants on 12 mg and 8.8% on 9 mg, compared to 0.7% on placebo (BioSpace, Dec 2025)

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[3] It also delivers copper ions for lysyl oxidase (which cross-links new collagen) and superoxide dismutase (an antioxidant defense enzyme)

The guidelines have not caught up