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Together, these effects help regulate appetite, stabilize blood sugar, reduce cravings and help address the biology of obesity, says Boyd

Overall, the ES paradigms affected behavior in 82.00% of the cases, this was consistent across the behavioral domains assessed (depressive-like behavior 82.35%, anxiety-like behavior 78.57%, cognitive deficits 85.00% and social deficits 80.00% and other ES-induced behaviors 90.00%)

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Further, human islet architecture has a more favourable organisation for paracrine signalling when compared with mouse islets [22, 31]