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As depicted in Table 4, exenatide exhibited the broadest spectrum, with a total of 8 potential signals indicating GLP-1 RA-induced AP, ranging from pancreatic abscess (ROR 4.20, 95% CI 1.0317.03) to pancreatic phlegmon (ROR 84.53, 95% CI 21.86326.90)
It is not approved by the FDA for clinical use
A more comprehensive understanding of these mechanisms may clarify the potential of GSH-degrading enzymes as targets for tumor diagnosis and therapeutic interventions
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But the FDA could soon approve these drugs for other conditions, which could make the costs of those drugs in Tennessee more expensive
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