Comprehensive ePRO Portfolio: We have experience in supporting a wide range of ePRO measures to assess aspects of health important to patients with these diseases including: Health-related quality of life (HRQoL, e.g., SF-36, Impact of Weight on Quality of Life-Lite (IWQoL-Lite)(EQ-5D-5L), Food craving (e.g., Control of Eating Questionnaire (CoEQ)), Mental health (e.g., Columbia-Suicide Severity Rating Scale (C-SSRS), Patient Health Questionnaire-9 (PHQ-9)) and other measures such as the Patient Global Impression of Severity/Change (PCIS/C)
The study lacked a young reference cohort
Patients with a history of pancreatitis require particular caution, as GLP-1 receptor agonists have been associated with rare cases of acute pancreatitis in clinical trials and post-marketing surveillance
Vegans and Vegetarians : Individuals following plant-based diets may be at a higher risk of B12 deficiency and can benefit from B12 supplementation through injections
Semaglutide (Ozempic, Wegovy) is not associated with increased yeast infection risk in clinical trials or FDA prescribing information
Magnesium lactate and magnesium chloride : These forms are also generally well-absorbed and may be suitable options