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This will affect about 10% of Medicare enrollees
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GLP-1 receptor agonists (GLP-1 RAs), primarily developed for their metabolic effects 68 , demonstrated neuroprotective activity in preclinical models over two decades ago 9 with subsequent studies revealing anti-inflammatory effects in both central and peripheral tissues 10
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The study assessed drug utilization and temporal changes in treatment options (e.g., SGLT2i, GLP-1 RA) in adults with CKD and type 2 diabetes regarding two time periods: an earlier period (1 January 201230 June 2021) and a later period after the US approval of finerenone (9 July 202130 September 2023), with the latter period representing updated treatment guidelines, changes to CKD drug labeling (e.g., SGLT2i), and the availability of new CKD-protective medications (ESM Fig
Similar content being viewed by others Introduction A progressive decline in skeletal muscle mass and strength, or sarcopenia, is increasingly recognized as a significant comorbidity in patients with type 2 diabetes mellitus (T2D) and obesity [1, 2]
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