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Production scalability poses additional constraints, 35 especially for cell therapies such as iPSC therapies, where patient-specific manufacturing increases production time and cost
Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
If the cyst remains, surgery may be recommended
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A large-scale study analyzing data from over 60 million patients finds no evidence that GLP-1 receptor agonists increase suicidality risk in type 2 diabetes patients, challenging previous safety concerns
The piece was updated in November 2025
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