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The distal end (S49 ECD ) of the helix was more mobile than the proximal one (E34 ECD ), which had an overall tendency to remain in the proximity of the TT-OAD2-binding site, driven by transient interactions with the ligand (Extended Data Table 1) and hydrogen bonds with the R299 ECL2 side chain (Extended Data Table 2)

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So if the concentration is 10mg per mL, then every 10 units (0.1 mL) equals 1mg of tirzepatide

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MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA

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