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PMID: 16539679 Khvatova EM, Samartzev VN, Zagoskin PP, Prudchenko IA, Mikhaleva II (2003) Delta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia
It is still unknown whether mutant SOD1 fibrils initiate ferroptosis by disrupting mitochondrial iron homeostasis, for example by promoting ironsulfur cluster release, or how lipid peroxidation products generated during ferroptosis (such as 4-HNE) accelerate TDP-43 nuclearcytoplasmic mislocalization and aggregation
Figure 2A)
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