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Poynten, A

Liver fibrosis progression is governed by bidirectional crosstalk between T cells and hepatic stellate cells (HSCs)

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"Some of my favorites include fatty fish, walnuts and flaxseeds," says Herring

In experimental models, researchers may explore processes such as angiogenesis-associated signaling, extracellular matrix organization, cellular migration, and immune-linked pathway activity

Interestingly, however, it is unclear if the sir1 phenotype could be fully restored by further inhibiting GCL activity and if the activation of glutathione synthesis in sir1 would exacerbate the growth phenotype