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No hGH Receptor Binding or IGF-1 Stimulation AOD9604 did not induce hyperglycaemia or reduce insulin secretion in sharp contrast to chronic intact hGH treatment and confirmed that the concept of hGH behaving as a pro-hormone is valid, with fragments capable of acting via mechanisms novel to traditional GH receptor-stimulated pathways

There is some evidence that L-carnitine may help preserve lean muscle mass during calorie restriction, though the data is mixed and the effect sizes are small

PMID: 37385275

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Most side effects reflect normal physiologic adaptation, while warning signs signal the need for provider evaluation