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Inoculation of -synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve

Migraines that are correlated with the menstrual cycle

Results Exogenous H 2 O 2 elicits compartmentspecific E GSH and H 2 O 2 responses Little is known about the dynamic handling of H 2 O 2 in the mitochondrial matrix of intact cells

Key Takeaway: Glutathione is the final protective molecule the body uses, while NAC is a primary building block used to create that molecule internally

Oxidative stress is crucial in atherogenesis (144151), suggesting that a specific antioxidant/prooxidant imbalance, characterized by a weak GSH-related enzymatic antioxidant shield present in human atherosclerotic lesions, may be involved in atherogenic processes in humans (152)

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