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In vitro release assays and in vivo pharmacokinetics in a diabetic rat model revealed ultra-sustained drug release with stable therapeutic plasma concentrations over six weeks, mirroring or surpassing the efficacy of conventional daily injections
Its primarily found in the modern diet in animal products, so vegans and vegetarians need to supplement with B 12 regularly
Diabetes Obes Metab (2019) 21(11):254252
Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, Yan Y, Sitaraman S, Merlin D
While oral supplements work for some, injections provide several distinct advantages: Immediate Absorption Directly enters the bloodstream, bypassing digestive barriers
More recent studies suggest some of its glucose-lowering effects may originate in the gastrointestinal tract rather than the liver
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