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Compared to placebo, GLP-1 receptor agonists reduced the risk of kidney failure by 16% and the worsening of kidney function by 22% (defined by a drop in estimated glomerular filtration ratea measure of how much blood the kidneys filter clean every minuteof at least 50%)

& Kuchay, M

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Upon ligand-receptor binding and depolarization, hormone-containing granules fuse with the lateral and basal membrane for discharge into the villus capillaries (Paternoster and Falasca, 2018)