Owing to their multi-target and synergistic pharmacological mechanisms, such as anti-inflammatory, membrane-stabilizing, antioxidant, anti-apoptotic, and immunomodulatory effects, they have demonstrated clear efficacy in the clinical treatment of various liver conditions, including viral hepatitis, drug-induced liver injury, and alcoholic liver disease
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In conclusion, using a low-carnitine tilapia model, the present study has shown that dietary l-carnitine can be physiologically utilised in fish, and it has the effect of reducing lipid accumulation in the liver
Beyond selection, safety biomarkers address another parallel concern
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Potential molecular mechanisms of ALCAR activity include: (1) acetylation of -NH 2 and -OH functional groups in amino acids and N terminal amino acids in peptides and proteins resulting in modification of their structure, dynamics, function and turnover