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It wasn't a huge problem for creators

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Key Fact #1: Age-Related Factors Affecting B12 Absorption Several things change with age that make it harder to absorb B12

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DOI: 10.1016/S0140-6736(23)01163-7

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BPC-157 upregulates angiogenic pathways (including VEGF) and counteracts inflammatory cytokines [3]

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Who Faces Elevated Risk: Several populations experience heightened B12 deficiency risk

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But losing 10-15% to freeze damage may be preferable to losing 70% to expiration at room temperature or refrigeration beyond 30 days

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