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Another study took place between September 2021 to late November 2022, in a total of 272 participants underwent adaptive randomization

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After switching from alogliptin 25 mg daily to dulaglutide 0.75 mg weekly, and reducing IDeg/Asp from 36 to 24 units/day while maintaining other antidiabetic drugs, glycemic control was effectively maintained during the subsequent hospitalization

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Circulating PYY 3-36 is derived from PYY 1-36 through DPP4-mediated cleavage of the N-terminal residues

These results justify guideline inclusion and support personalized treatment plans in clinical practice