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"Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis." Clinical Nutrition ESPEN

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As intracellular GSH is exhausted, the GSH synthesis system will be activated accordingly, which would weaken the efficacy of GSH exhaustion-based cancer therapies in long-term treatment (Xiong et al., 2021)

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We hypothesized that combination drug therapy, covering each different mechanism of drug action, may be more effective to ameliorate or prevent deterioration of the disease

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