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The durability of weight loss effects has been examined in the SURMOUNT-4 trial (Rubino et al., JAMA 2023), which demonstrated that discontinuation of tirzepatide after successful weight loss led to significant weight regain, suggesting ongoing treatment may be necessary for sustained benefits

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Ansa cervicalis stimulation: a new direction in neurostimulation for OSA

Retatrutide vs tirzepatide is one of the most obvious comparison questions in current peptide research, but it is also one of the easiest to mishandle

doi:10.1097/01.ten.0000127932.31710.4f Brennan MD, Powell C, Kaufman KR, Sun PC, Bahn RS, Nair KS

This can lead to increased nausea, bloating, and other gastrointestinal issues