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The related pathways of HMGCR in tumor progression are summarized in Figure 2
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Ultimately, persistent fibrosis, progressive inflammation, and maladaptive renal repair compromise glomerular function, exacerbating toxin retention, oxidative imbalance, and the self-perpetuating cycle of renal decline (93)
Treating 0.25mg as 0.25mcg would result in massive overdose
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