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Surprisingly, multiple ALS-causative mutations in FUS/TLS increase FUS/TLS interaction with SMN, thereby affecting the normal function of SMN by both reducing Gem bodies and changing steady-state levels of some snRNAs in transgenic mouse tissues and patient fibroblasts expressing mutant FUS/TLS
Shah, A
F., Grant, W
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Licensed injectable GLP-1 receptor agonists such as semaglutide and dulaglutide are available for appropriate patients through NHS prescribing
M., & Belykh, A
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