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Editorial Advisory Board Member, Harvard Health Publishing The GLP-1 drugs, which include semaglutide (Ozempic, Rybelsus, Wegovy) and tirzepatide (Mounjaro, Zepbound), are turning out to have effects that go beyond shedding pounds and controlling diabetes

Retatrutide, if approved in future, would represent a potential addition to this landscape but that determination rests on the outcome of ongoing phase 3 research and subsequent regulatory review by the MHRA and EMA

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Decreased glucagon-like peptide 1 receptor expression in endothelial and smooth muscle cells in diabetic db/db mice: TCF7L2 is a possible regulator of the vascular glucagon-like peptide 1 receptor

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