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Summary: Excessive vitamin B12 intake rarely causes toxicity, but very high levels from supplements or injections may be associated with skin reactions such as acne-like eruptions, though serious adverse effects remain exceptionally uncommon
The initial phase of treatment usually involves higher and more frequent doses to quickly restore healthy vitamin B12 levels
A review on BPC 157 was published in Current Reviews in Musculoskeletal Medicine in August 2025, acknowledging the potential benefits and unknown long term risks but noted that no adverse effects have been reported to date in available studies
The Bottom Line GLP-1 and BPC-157 are not interchangeable
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