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Another recently completed phase 3 clinical trial called REDEFINE 2 , which included 1,207 adults with type 2 diabetes and overweight or obesity, found that after 68 weeks, CagriSema led to weight loss of almost 16% experts say the highest yet in the type 2 population, compared to other weight management drugs like tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) and semaglutide

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D., McDonough, J

Beyond sequence, epigenetic evidence points to an NNMT-linked signature in human adipose tissue, indicating the pathway is dynamically active in human fat biology, not only in laboratory animals

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