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It acts a lot like a blender, as it grinds and mashes the material that we eat
Studies showed that people taking the pill lost a significant amount of weight, similar to results seen with weekly injections
The mechanisms responsible for these effects are not entirely clear, but the slowing of gastric emptying may be the key driver
Once absorbed, it converts enzymatically, first to retinaldehyde, then to retinoic acid, which binds nuclear retinoic acid receptors (RARs) and drives cell-level changes
Mol Cell Biochem 395(12):110
doi: 10.1089/dia.2023.0320 7 LeslieRDEvans-MolinaCFreund-BrownJBuzzettiRDabeleaDGillespieKmet al
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