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Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome
Primer on Cerebrovascular Diseases
New York: Simon & Schuster (2000)
In a 24-week extension study, the treatment response rates for 5 mg, 10 mg, and 20 mg doses were 40%, 50%, and 45%, respectively, compared to a 25% response rate for the placebo
Soft keratin present in the horny layer of the epidermis, containing between 2 and 4% L-cystine and hard keratin , present in the nails and hair, containing between 14 and 18% L-cystine
The GSH/GSSG ratio usually indicates the level of cellular oxidative stress, which accelerates the conversion of GSH to GSSG and decreases the GSH/GSSG ratio [26]
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