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Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo
-glutamyl conjugates and N acetyl -glutamyl conjugates Due to the tissue distribution of GT, -glutamyl prodrugs have been mostly developed for kidney applications
is supported by UL1 TR001866 from the National Center for Advancing Translational Sciences (NCATS, National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) programme
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets
Some users find they respond well to lower doses and never need to reach the peak phase amounts
Edwick et al
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