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Glutathione is the main antioxidant in the body that is required for smooth cellular functioning
They bind to GLP-1 receptors located in the pancreas, brain, and gastrointestinal tract
Earlier studies demonstrated that GSH depletion could induce apoptosis 19,20 or necrosis 21 in RPE cells
However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]
By age 60, that level falls to about 80 ng/mL
PMID 16787421
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