No receptor desensitization problem has been established for it
Microsomal GSTs belong to the MAPEG family (membraneassociated proteins in eicosanoid and glutathione metabolism), which play a significant role in the reduction of lipid peroxidation and xenobiotic detoxification [62, 63]
Studies have found that dietary glutathione isnt actually associated with glutathione levels in the blood, and supplementing with glutathione is an extremely inefficient (and expensive) way to raise glutathione levels by a very small amount
The researchers initially attributed the drugs success in mouse studies to its ability to reduce or eliminate androgen receptors in the prostate cancer cells
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Prasad A, Andrews NP, Padder FA, Husain M, Quyyumi AA