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Obviously, the ECD of the closed conformation prevents GLP-1 binding and further experiments are necessary to fully understand the functional impact of the closed ECD conformation on Gs binding

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doi: 10.3389/fphar.2024.1483792 Received 20 August 2024 Accepted 23 December 2024 Published 20 January 2025 Volume 15 - 2024 Edited by Ewa Krystyna Szczepanska-Sadowska, Medical University of Warsaw, Poland Reviewed by Per M

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