The logic is that local administration creates higher peptide concentrations at the relevant tissue
Supports gastric-ulcer healing and intestinal balance
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This movement, called migration, is heavily dependent the protein actin
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Co-culture models that combine distinct hiPSC-derived cell types to replicate key aspects of the BBB exhibit physiologically appropriate characteristics including tube formation, organized tight junctions with acceptable transendothelial electrical resistance (TEER), expression of active transporters, and uptake of low-density lipoprotein (Lippmann et al., 2012