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For individuals with pernicious anaemia or a condition that prevents B12 absorption, injections are medically necessary because oral supplementation will not be absorbed effectively
Tirzepatide is FDA-approved
(See: Are compounded GLP-1 medications covered by insurance
So insulin is kind of preventing high blood sugar and glucagon is preventing low blood sugar by telling the liver and effect keep pumping out glucose
Int J Mol Sci 21(19):7431
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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