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For 10 weeks, participants were put on a very low-calorie diet along with exercise

Unger J, Kaltoft M, Kolhe D, Panda JK, Sargin ME, Wolthers BO, Zoghbi M

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Skibicka et al., 2011

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Individuals with the MTHFR gene variation and high homocysteine levels may also benefit from B2 (riboflavin), as well as activated versions of folate, B6 , and B12 , such as methylated folate (also known as L-5-MTHF Folate, methylfolate, 5-formyltetrahydrofolate or NatureFolate), Pyridoxal-5-Phosphate (P5P), and methylcobalamin, respectively