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Evans SF, Hull ML, Hutchinson MR, Rolan PE
Butyrate inhibits the HDAC8/NF-B pathway to enhance Slc26a3 expression and improve the intestinal epithelial barrier to relieve colitis
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Product Specifications CAS Number: 189691-06-3 Peptide Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1) Molecular Formula: CHNO Molecular Weight: 1025.182 g/mol Subcategory: Sexual Health & Hormonal Peptides Purity: 95% (verified by HPLC) Packaging Format: 5 mg lyophilized powder in sealed research-grade vial Storage Conditions: Store at 28 C or frozen at 20 C as appropriate
In contrast, when placed under metabolic stress with increased demand on the -cell (induced by high fat feeding and a low dose of the -cell toxin, streptozotocin), glucose tolerance did become impaired, supporting the view that paracrine GLP-1 may be required to maintain glucose homeostasis during adaptation to metabolic stress (114)
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