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In terms of how soon: some effects (like improved alertness) can be within a few days
However, this is not the case because the body absorbs B12 oral supplements and injections differently
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An injection delivers B12 directly into the muscle, so absorption does not depend on your digestive system
in this form it is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine (a reaction which also requires folate)
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