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While App knockin mouse shows no significant neurodegeneration and neuronal loss, it shows synaptic loss and reduction of a part of neuronal cells including active place cells around A plaques 41,60
Adverse drug reactions of GLP-1 agonists: A systematic review of case reports
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Important limitations remain: The human studies are small
Studies show that weight loss with GLP-1 therapy results in improved left ventricular function and reduced left ventricular mass, enhancing overall cardiac performance
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