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10.3389/fendo.2024.1378291 68 XiongL.GuoH.-H.PanJ.-X.RenX.LeeD.ChenL.et al (2024)

People taking GLP-1s may experience fewer blood sugar spikes, less hunger, and quicker, longer-lasting fullness after meals

48 Similar results were obtained in a hGLP-1R knock-in murine model in which the administration of Danuglipron resulted in an overall improvement of glucose tolerance and food intake reduction, thus opening the possibility to use an effective oral GLP-1RA

Cook points to his own experience

We also evaluated acute treatment with tirzepatide, a dual GLP-1/gastric inhibitory peptide (GIP) receptor agonist, and retatrutide, a triple GIP/GLP-1/glucagon receptor agonist, to determine whether broader receptor activity would differentially influence alcohols subjective effects

The difference is the target