Management narrowed full year 2025 revenue guidance to approximately $2.335 billion to $2.355 billion and adjusted EBITDA guidance to $307 million to $317 million
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They could also be used as part of a flexible step-up or step-down strategy
In human kidneys, GLP-1R has been identified as localized to proximal renal tubule cells and preglomerular vascular smooth muscle cells (191)

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