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The Billon 2025 paper introducing SLU-PP-915 (PMID 41421047) describes the parent compound SLU-PP-332 as lacking oral bioavailability the orally active sibling SLU-PP-915 was developed because of that limitation
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Similarly, research has demonstrated that polyphenolic compounds maintain significant antioxidant effects in vivo , as evidenced by enhanced plasma antioxidant capacity and reduced markers of oxidative stress in animals supplemented with polyphenols (364)
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It is formulated with hydrolysed collagen types 1 and 3 and the reduced active form of glutathione for optimal bioavailability
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