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Description

Keywords: Akkermansia muciniphila

The condition creates a frustrating cycle where insulin resistance promotes weight gain, and weight gain worsens insulin resistance and hormonal imbalance

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These observations prompted us to investigate the expression and function of incretin hormones in monotremes

We provide evidence that this targeting concept can be used to antagonize NMDA receptors specifically in GLP-1-receptor-positive neurons to reverse obesity and correct symptoms of cardiometabolic diseases in preclinical obesity models