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MYC and MCL1 cooperatively promote Chemotherapy-Resistant breast Cancer stem cells via regulation of mitochondrial oxidative phosphorylation
The increased expression of SNAIL, in conjunction with EMT, triggers metabolic reprogramming in cancer cells, which is characterized by increased glucose absorption and lactate generation, as well as decreased mitochondrial respiration [292, 293]
Oxygen and glucose deprivation (OGD) model and cell viability To imitate the in vivo environment of ischemia and hypoxia after fat transplantation, ADSCs were cultured under hypoxic and glucose-free conditions to induce an OGD model
Human evidence remains limited to small panels and cosmetic-grade applications
As a result, the M1/M2 classification fails to fully capture the range of functional states exhibited by TAMs in ovarian cancer (134)
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