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This rapidly increasing obesity burden continues strengthening demand for semaglutide-based weight management therapies globally

Although exciting, these data are preliminary and there is a need to learn more

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The remaining 30-40% have mild to moderate persistent constipation that requires ongoing management with dietary changes or laxatives

Early responders who lost at least 15 percent of their body weight by week 24 went on to achieve an incredible 27.7 percent mean weight loss by week 72 (Source: STEP UP Trial, Dicker et al., ECO Abstract 2026)