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MASLD represents a continuum of chronic liver disorders, ranging from simple steatosis to more advanced stages, such as metabolic dysfunction-associated steatohepatitis (MASH, formerly known as NASH) (1)

Owen MJ, Sawa A, Mortensen PB

doi: 10.2337/dc11-0096 64 GuytonJJeonMBrooksA

What questions should I ask the clinician before starting

Maintaining the same caloric deficit you had on tirzepatide without accounting for the additional expenditure can push you into an excessive deficit that promotes muscle loss, fatigue, and metabolic adaptation

This occurs purely from reduced caloric intake driven by the medication's appetite-suppressing effects