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It has a solid safety profile when prescribed and monitored by a medical provider
In addition, there was upregulation in the expression of the proinflammatory cytokine Tnf and genes involved in the integrated stress response ( Atf3 , Atf5 , Ddit3 and Dele1 ) and reduced expression of the adipokine Adipoq
Changes in renal function may also occur in patients experiencing significant weight loss, as glomerular hyperfiltration associated with obesity improves
Evidence Level [EL] 1)
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