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Arginase 1 (cytosolic isoform) expression in MDSCs is also important for the suppressive function of these cells, restraining Teffs-mediated antitumor immunity and promoting both Teffs cell death and Tregs suppressive effects [85, 86]

Compartment-specific real-time measurements based on genetically encoded fluorescent probes now suggest that the cytosolic glutathione redox potential is about 100 mV more reducing than previously thought

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Goat Anti-Mouse IgG - HRP Secondary Antibody (HA1006) at 1/50,000 dilution was used for 1 hour at room temperature

Cell Metab 2022;34:1064-78.e6.ArticlePubMedPMC 126