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The main differences across comparison categories are: Mechanism of Action: advantage goes to NAD+
GLP-1 is part of the bodys incretin system, which helps regulate blood sugar after eating and influences appetite and digestion
Combining them would increase side effect risk without adding meaningful efficacy
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The Results In this study, 3,346 people with obesity, meaning a BMI over 30, but without diabetes started GLP-1 therapy and were compared to 8,343 similar people not using GLP-1 drugs
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