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Jigeer G, Tao W, Zhu Q, et al

The most common side effects with topical use include mild redness, temporary stinging at application site, and initial purging (worsened appearance before improvement)

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Unique Features: Semaglutide is the first GLP-1RA shown to reduce cardiovascular events in non-diabetic individuals, making it a notable choice for obesity management

Findings suggest that the peptide may support vascular adaptation by encouraging the development of new microvascular networks, a process that can improve perfusion in tissues exposed to reduced blood supply

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