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"American Diabetes Association Highlights Novel Agent Retatrutide Results in Substantial Weight Reduction for People with Obesity and Type 2 Diabetes During Late-Breaking Symposium." diabetes.org, Accessed July 10, 2023, Lancet Diabetes & Endocrinology
For most of them (e.g., the cardiac glycosides), the clinical development will be limited due to their toxicity associated with expected side effects in human
Results Semaglutide treatment resulted in a significant weight reduction at one year, with a mean BMI decrease of 2.23 kg/m 2 (95% CI 2.71 to 1.75
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BMJ 2021;372:m4573