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A thinner needle (higher gauge) causes less discomfort but draws medication more slowly, which is why many patients use a wider drawing needle and switch to a thinner needle before injecting

[3] Next-Generation Dual and Multi-Targeted Therapies on the Rise Amycretin: A Promising Dual GLP-1/Amylin Receptor Agonist Also making headlines at ADA 2025 was Amycretin (NNC0487-0111), a novel, unimolecular GLP-1 and amylin receptor agonist under development by Novo Nordisk